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Sepsis patient in hospital

Help create the Adaptive Platform for Sepsis Care

Help us stop sepsis before it steals another life. Your gift today can save lives by enabling faster detection, smarter treatment, and lasting recovery.
Associate Professor Naomi Hammond and Associate Professor Anthony Delaney
Royal North Shore Hospital
16 Projects
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$4,930,000
$0
$4,930,000

Help stop the clock on sepsis

Sepsis is one of the world’s most urgent and under‑recognised medical emergencies. It can kill within hours, and every hour treatment is delayed increases mortality by up to 9%. At Royal North Shore Hospital, intensive care specialists are launching the Sepsis Adaptive Platform – a connected model spanning early detection, rapid treatment, and long‑term recovery, powered by a Single Digital Patient Record.

Your support will help us detect sepsis earlier, deliver the best treatments faster, and support survivors for the long haul. The Sepsis Adaptive Platform tackles the full spectrum of sepsis care: from recognising danger sooner, to learning which treatments work best for each patient, to ensuring survivors are supported months and years after hospitalisation.

Your gift will:

  • Accelerate real‑time detection and clinical alerts
  • Expand adaptive clinical trials across NSW
  • Reduce deaths, disability, and hospital readmissions
  • Build integrated rehabilitation services for sepsis survivors
  • Share a scalable model nationally and internationally

“There is no magic bullet for treating sepsis. The treatments we have in ICU provide supportive care.”

– Associate Professor Naomi Hammond – Executive Director of Research, Northern Sydney Local Health District


Sepsis: a silent killer, hiding in plain sight

1 in 7 global deaths

are caused by sepsis.

55,000 Australians each year

are affected by sepsis, resulting in 26,000 ICU admissions and 8,700 deaths.

Up to 9% higher mortality

occurs for every hour sepsis treatment is delayed.

Sepsis is the body’s extreme response to infection, triggering organ failure and death if not treated fast. Mortality rises for every hour treatment is delayed, and around 35% of all in‑hospital deaths involve sepsis. Survivors often face disability, cognitive decline, PTSD, and frequent readmissions – with up to 70% readmitted within a year.

Care is fragmented. Patients move between GPs, Emergency Departments and hospitals, while vital information sits across separate systems – causing delays that can be deadly. And after discharge, survivors often face a maze of services with no unified recovery pathway.

A new approach to saving lives

To combat this deadly disease, our specialist sepsis research team at Royal North Shore Hospital is launching the Sepsis Adaptive Platform – a connected program transforming how we detect, treat, and support sepsis patients.

Pillar 1: Early Detection & Prevention
Build a real-time alert system through the Single Digital Patient Record to spot sepsis early and guide best-practice care across NSW, in any hospital or Emergency Department.
Pillar 2: Adaptive Platform Trial
Test multiple treatments at once and quickly learn what works best for different patients, feeding results straight into care as evidence emerges.
Pillar 3: Physical & Mental Rehabilitation
Provide coordinated post-sepsis follow-up that supports survivors’ physical, cognitive and psychological recovery, long after discharge.

“With sepsis we want to find the best ways of supporting people’s vital organ function… and then integrate those treatments.”

 Associate Professor Anthony Delaney – Senior Staff Specialist, Intensive Care Unit, Royal North Shore Hospital

Associate Professor Anthony Delaney with Jacob

Patient with sepsis in hospital bed
Jacob’s story

“It changed my life entirely.”

A small puppy scratch led to septic shock and multiple organ failure. Jacob Dye spent weeks in intensive care and months in recovery. Like many survivors, he experienced lasting physical and psychological impacts – and now, as a senior researcher, he is helping shape the future of sepsis care through this program. 

“I went from perfectly healthy to being at death’s door.”

– Jacob Dye, sepsis survivor 

 

Support the Adaptive Platform for Sepsis Care

What your support funds

Your support will have a transformational impact on improving prevention, survival, and long‑term recovery for people facing sepsis. Longer term, it will improve the physical, psychological and cognitive challenges survivors live with, and lift post‑sepsis survival and quality of life. The potential health and economic benefits are immense.

Funding breakdown:

  • Personnel & data management: $2.56m
  • Patient & site payments: $2.24m
  • Operational costs: $0.13m

“The ability to identify someone early and follow them through with effective care could be transformative for patient outcomes.”

– Associate Professor Naomi Hammond

 

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