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Support the research of Professor Lopez-Escamez at the Kolling Institute

World leading Meniere’s disease researcher Professor Jose Antonio Lopez Escamez has recently relocated from Spain to the Kolling Institute.

He’s developing breakthroughs with this complex disease and has launched an exciting new research program. His work will use stem cells to investigate inflammation linked to the disease. It is hoped that his research will give us a better understanding of the molecular mechanisms of the disease, including the role of genetics.

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Professor Jose Antonio Lopez Escamez lab photo

What is Meniere’s disease?

Meniere’s disease is a rare disease of the inner ear that causes vertigo, sensory neural hearing loss and tinnitus, and it may be associated with systemic inflammation and alteration of the inflammatory response.

Tinnitus disorder is a debilitating condition that may lead to severe disability. Patients with severe tinnitus also show high frequency hearing loss and mild cognitive impairment. Severe tinnitus has a genetic contribution and there is a load of rare variation in certain synaptic genes that may explain the association of hearing loss, tinnitus and cognitive impairment.

Professor Jose Escamez photo

Research focus

Professor Lopez-Escamez’s research work focuses on understanding the cellular and molecular bases of Meniere’s disease and tinnitus disorder.

His studies across the genomics of Meniere’s patients have identified several genes in familial cases, including OTOG, TECTA and MYO7A genes, raising a new hypothesis to explain the onset of the condition.

Why support Professor Lopez-Escamez

Jose Antonio López Escámez leads the Meniere-Neuroscience Laboratory at the Kolling Institute. His research focuses on the influence of family heritage in Meniere’s disease and the study of new genes linked to Meniere’s disease.

Professor Lopez-Escamez is a visiting scholar at the University of Granada, Spain and is Principal Investigator at the Otology & Neurotology-Genomic Vestibular Disorders Group at the Centre for Genomics and Oncology Research (GENyO) and Bio sanitary Research Institute.

He has been Chair of Otorhinolaryngology at the Royal Academy of Medicine in Eastern Andalusia since 2013 and is ranked in the top 2% of the 2022 Stanford World Scientists magazine.

He was Scientific Director of ibs. Granada, from May 2018 until December 2020, one of the largest Health Research Institutes in Spain with more than 1000 affiliated researchers. As supervisor, he has mentored 24 masters and 10 PhD students.

How much would you like to donate?

By donating today, you will be helping understand the cellular and molecular bases of Meniere’s disease and tinnitus disorder.

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