As a non-smoker, Natarajan never imagined he would be diagnosed with lung cancer.
In October 2012, after months of persistent coughing, a CT scan revealed the devastating news that Natarajan had stage four lung cancer. The disease had metastasised, where cells from the primary tumour break off, and new tumours were discovered in his brain and liver.
Further tests revealed Natarajan had Anaplastic Lymphoma Kinase (ALK) – positive lung cancer – a rare form of cancer caused by a mutation of the ALK gene.
He was referred to Royal North Shore Hospital (RNSH), under the care of medical oncologist Professor Nick Pavlakis and his multidisciplinary team of healthcare professionals. They were able to offer Natarajan more than a comprehensive range of treatments and support in treating his cancer – they offered hope.
Lifesaving surgery and a fighting chance
The following month, neurosurgeon Dr Nicholas Little performed delicate brain surgery to remove the tumour on Natarajan’s left temporal lobe. Natarajan then commenced six months of intensive chemotherapy.
After all he had endured, a follow-up scan revealed the tumour was slowly growing again, and Natarajan was offered a place in a clinical trial for targeted drug therapy. The results were encouraging, and it was a turning point in his treatment.
“Cancer clinical trials are more than carefully designed research studies. They are lifelines, aimed at uncovering new ways to prevent, detect and treat the disease.”
The drugs kept the cancer under control and aside from a temporary loss of taste, he felt well and hopeful.
When the tumour began growing again a year later, ongoing medical research made another targeted therapy available. The treatment proved effective, and he remained on medication for five years.
In September 2014, when a growth was found in his lung, cardio-thoracic surgeon Dr Manu Mathur performed an eight-hour procedure to remove the lower left lobe. Recovery was challenging but with the help of shallow breathing exercises, Natarajan was able to manage his pain and regain strength.
In 2019, another tumour was detected dangerously close to his optic nerve. While surgeons successfully removed the lesion, the procedure impacted his mobility. An intensive six-week rehabilitation program helped him reclaim most of his independence.
The Northern Sydney Cancer Centre (NSCC) played a crucial role in his recovery, introducing physiotherapy to help ease the stiffness and pain caused by the medication’s side effects. During COVID, the NSCC recommended online yoga and meditation classes, giving him practical tools to build strength and ease anxiety.
Cancer clinical trials are Natarajan’s lifeline
Since 2020, Natarajan has been on a targeted therapy drug that stops cancer cells from growing and spreading. What began as a single drug option when he first commenced the trial program over a decade ago, has now expanded into multiple avenues for treatment.
Natarajan is grateful for the support from his clinical team, including a dedicated clinical trials nurse, as well as his oncologist, whose optimism and determination have been a source of strength.
“Professor Pavlakis is very positive,” says Natarajan. “Whenever I feel like giving up, he’ll say we’re going to challenge it and try a little more.”
Natarajan values the open communication he has with his care team and appreciates being part of a learning journey that informs future treatments for others as well. His interactions with medical students give him purpose, knowing that he is contributing to the future of cancer care and other patients in their fight against the disease.
Remarkably, when comparing scans from a decade ago, Natarajan is elated that his cancer hasn’t spread. Despite living with a chronic condition, he remains proactive – managing his medications and attending regular check-ups at RNSH. Natarajan also practices pranayama, an ancient Indian discipline focused on breath control, physical postures and meditation, helping cultivate calm and mental clarity.
Now retired, he cherishes time with his wife, two children and two grandchildren and can look to the future and visiting family in Chennai, India.
Support the future of cancer care
Natarajan’s story is a reminder of the impact that research, clinical trials and compassionate care can have on a person’s life.
Deeply grateful to his healthcare team and the medical research that made it possible, Natarajan gives back by donating to cancer research through the NORTH Foundation that will help to accelerate discoveries and improve outcomes for others.
If you would like to help fund vital research and bring hope to more patients and families facing cancer, please donate below.
